Doramectin

Antiparasitics

An endectocide of the macrocyclic lactone (avermectin) class. It binds to glutamate-gated chloride channels in parasites, paralyzing and killing them. It is effective against roundworms and arthropods in livestock.

Drug class
Antiparasitics
Registered species
2
Recorded effects
0
Related products
4

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

An endectocide of the macrocyclic lactone (avermectin) class. It binds to glutamate-gated chloride channels in parasites, paralyzing and killing them. It is effective against roundworms and arthropods in livestock.

Indications

  • Gastrointestinal and lung roundworms
  • Warbles (grubs), mange, and lice

Contraindications & warnings

  • Adherence to withdrawal periods in food animals
  • Highly toxic to aquatic organisms — avoid contaminating water with its residues

Drug interactions

  • Its neurological effect may be aggravated by drugs that enhance GABA activity

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Dectomax 5 mg/ml Pour-on Solution for Cattle
Pour-on solution · C&H Generics Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle35 days——
Dectomax 10 mg/ml Solution for Injection for Cattle and Sheep
Solution for injection · C&H Generics Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle70 days——
Sheep70 days——
Doramax 10 mg/ml Solution for Injection for Cattle and Sheep
Solution for injection · C&H Generics Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle70 days——
Sheep70 days——
Doramax 5 mg/ml Pour-on Solution for Cattle
Pour-on solution · C&H Generics Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle35 days——

Recorded adverse effects

openFDA veterinary reports — the numbers are report counts, not a severity rate.

No adverse-effect data recorded for this ingredient yet.