Firocoxib
Anti-inflammatories & AnalgesicsA coxib-class non-steroidal anti-inflammatory drug (NSAID), selective for inhibiting cyclooxygenase-2 (COX-2), which drives inflammation, while relatively sparing the gastro- and reno-protective COX-1. It is used for osteoarthritis in dogs and horses.
Pharmacological information
A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.
Mechanism of action
A coxib-class non-steroidal anti-inflammatory drug (NSAID), selective for inhibiting cyclooxygenase-2 (COX-2), which drives inflammation, while relatively sparing the gastro- and reno-protective COX-1. It is used for osteoarthritis in dogs and horses.
Indications
- Pain and inflammation associated with osteoarthritis
Contraindications & warnings
- Peptic ulcer, renal or hepatic impairment, and dehydration
- Caution in very young and pregnant animals
Drug interactions
- Not combined with other NSAIDs or corticosteroids
- Caution with nephrotoxic drugs and diuretics
Withdrawal periods
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Horses | 26 days | — | — |
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Horses | 26 days | — | — |
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Horses | 26 days | — | — |
Recorded adverse effects
openFDA veterinary reports — the numbers are report counts, not a severity rate.
Dogs
Horses
Related products
Sources
- •Withdrawal periods: UK Veterinary Medicines Directorate (VMD).
- •Adverse effects: the openFDA veterinary database.
- •European Medicines Agency (EMA) — Veterinary medicines
- •Merck Veterinary Manual — Pharmacology
- •Always verify the locally approved leaflet and consult a veterinarian.