Florfenicol
AntibioticsA phenicol antibiotic that binds to the 50S ribosomal subunit, inhibiting bacterial protein synthesis. It does not carry the risk of aplastic anemia associated with chloramphenicol.
Drug class
Antibiotics
Registered species
1
Recorded effects
0
Related products
7
Pharmacological information
A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.
Mechanism of action
A phenicol antibiotic that binds to the 50S ribosomal subunit, inhibiting bacterial protein synthesis. It does not carry the risk of aplastic anemia associated with chloramphenicol.
Indications
- Respiratory disease in cattle and pigs caused by susceptible bacteria (such as Mannheimia and Pasteurella)
Contraindications & warnings
- Not to be used in animals whose milk is intended for human consumption, per its approved labels
- Generally not used in breeding males, per some labels
- Caution in hepatic or renal impairment
Drug interactions
- Theoretical antagonism with beta-lactams and other bactericidal antibiotics (as the phenicol is bacteriostatic, weakening bactericidal agents that need actively dividing bacteria)
Prudent use of antibiotics
Prescribed based on diagnosis and susceptibility testing where possible, to limit antibiotic resistance.
Withdrawal periods
Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Norfenicol 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Norbrook Laboratories Limited
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 44 days | — | — |
Resflor 300/16.5 mg/ml Solution for Injection for Cattle
Solution for injection · Intervet International B.V.
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 46 days | — | — |
Nuflor Minidose 450 mg/ml Solution for Injection for Cattle
Solution for injection · Intervet International B.V.
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 64 days | — | — |
Zeleris 400 mg/ml + 5 mg/ml Solution for Injection for Cattle
Solution for injection · Ceva Animal Health Ltd
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 56 days | — | — |
Selectan 300 mg/ml Solution for Injection for Cattle and Swine
Solution for injection · Laboratorios Hipra SA
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 30 days | — | — |
Flordofen 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Dopharma Research B.V.
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 44 days | — | — |
Nifencol 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Vetpharma Animal Health, S.L
| Species | Meat | Milk | Eggs |
|---|---|---|---|
| Cattle | 30 days | — | — |
Recorded adverse effects
openFDA veterinary reports — the numbers are report counts, not a severity rate.
No adverse-effect data recorded for this ingredient yet.
Related products
Norfenicol 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Norbrook Laboratories Limited
Resflor 300/16.5 mg/ml Solution for Injection for Cattle
Solution for injection · Intervet International B.V.
Nuflor Minidose 450 mg/ml Solution for Injection for Cattle
Solution for injection · Intervet International B.V.
Zeleris 400 mg/ml + 5 mg/ml Solution for Injection for Cattle
Solution for injection · Ceva Animal Health Ltd
Selectan 300 mg/ml Solution for Injection for Cattle and Swine
Solution for injection · Laboratorios Hipra SA
Flordofen 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Dopharma Research B.V.
Nifencol 300 mg/ml Solution for Injection for Cattle and Pigs
Solution for injection · Vetpharma Animal Health, S.L
Sources
- •Withdrawal periods: UK Veterinary Medicines Directorate (VMD).
- •European Medicines Agency (EMA) — Veterinary medicines
- •Merck Veterinary Manual — Pharmacology
- •World Organisation for Animal Health (WOAH) — Prudent use of antimicrobials
- •Always verify the locally approved leaflet and consult a veterinarian.