Ketamine

Anaesthetics & Sedatives

A dissociative anesthetic that acts as an NMDA-receptor antagonist, producing a state of anesthesia with loss of pain sensation while some reflexes persist. A controlled substance in many countries.

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Drug class

Anaesthetics & Sedatives

Registered species

Recorded effects

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

A dissociative anesthetic that acts as an NMDA-receptor antagonist, producing a state of anesthesia with loss of pain sensation while some reflexes persist. A controlled substance in many countries.

Indications

Induction and maintenance of anesthesia, usually in combination with a sedative (an alpha-2 agonist or a benzodiazepine)

Contraindications & warnings

Not usually used alone — may cause muscle rigidity and convulsions
Caution in heart disease, raised intracranial pressure, and hepatic or renal impairment

Drug interactions

Synergy with other central nervous system depressants

Human-safety warning

A controlled substance with potential for abuse; it is stored and documented under narcotics regulations, and handling precautions are taken to avoid accidental exposure.

Sources: European Medicines Agency (EMA) — Veterinary medicines·Merck Veterinary Manual — Pharmacology

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.

Nimatek 100 mg/ml Solution for Injection for Dogs, Cats and Horses

Solution for injection · Eurovet Animal Health B.V.

SPC leaflet ↗