A local anesthetic of the amide class. It blocks voltage-gated sodium channels in nerve membranes, preventing the generation and conduction of nerve impulses, producing local anesthesia. It also has use as an antiarrhythmic agent.

Drug class
Anaesthetics & Sedatives
Registered species
1
Recorded effects
0
Related products
1

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

A local anesthetic of the amide class. It blocks voltage-gated sodium channels in nerve membranes, preventing the generation and conduction of nerve impulses, producing local anesthesia. It also has use as an antiarrhythmic agent.

Indications

  • Local and regional anesthesia for surgical procedures
  • Control of some cardiac (ventricular) arrhythmias

Contraindications & warnings

  • Not to be injected directly into blood vessels when used for local anesthesia
  • Overdose may cause convulsions and cardiac depression — cats are more sensitive
  • Avoid preparations containing a vasoconstrictor (epinephrine) in terminal extremities

Drug interactions

  • Cardiac toxicity is aggravated with other antiarrhythmic drugs
  • Enhanced central depression with sedatives

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Ekyflogyl 1.8mg/ml + 8.7mg/ml Gel for Horses
Gel · AUDEVARD
SPC leaflet ↗
SpeciesMeatMilkEggs
Horses———

Recorded adverse effects

openFDA veterinary reports — the numbers are report counts, not a severity rate.

No adverse-effect data recorded for this ingredient yet.

Sources