Oxytetracycline

Antibiotics

A broad-spectrum, bacteriostatic tetracycline antibiotic. It binds to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA and halting bacterial protein synthesis.

Drug class
Antibiotics
Registered species
3
Recorded effects
0
Related products
8

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

A broad-spectrum, bacteriostatic tetracycline antibiotic. It binds to the 30S ribosomal subunit, preventing the attachment of aminoacyl-tRNA and halting bacterial protein synthesis.

Indications

  • Respiratory and systemic infections caused by susceptible bacteria
  • Intracellular pathogens (such as Chlamydia and Anaplasma)
  • Some cases of eye infection

Contraindications & warnings

  • Deposits in growing bones and teeth, causing discoloration — avoided as far as possible in very young and pregnant animals
  • Caution in renal or hepatic impairment
  • Hypersensitivity to tetracyclines

Drug interactions

  • Its efficacy is negated by divalent and trivalent cations (calcium, magnesium, iron, aluminum) through the formation of non-absorbable complexes
  • Theoretical antagonism with bactericidal beta-lactam antibiotics

Prudent use of antibiotics

Prescribed based on diagnosis and susceptibility testing where possible, to limit antibiotic resistance.

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Alamycin LA 300 Solution for Injection 300 mg/ml
Solution for injection · Norbrook Laboratories Limited
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle28 days8 days—
Sheep28 days8 days—
Alamycin LA 200 mg/ml Solution for Injection for Cattle, Sheep and Pigs
Solution for injection · Norbrook Laboratories Limited
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle41 days8 days—
Sheep24 days7 days—
Hexasol LA Solution for Injection for Cattle
Solution for injection · Norbrook Laboratories Limited
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle35 days——
Cyclosol LA, 200 mg/ml Solution for Injection
Solution for injection · Eurovet Animal Health B.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle35 days8 days—
Hypersol 500 mg/g Powder for Use in Drinking Water
Powder for use in drinking water · Huvepharma SA
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens7 days——
Terramycin/LA 200 mg/ml Solution for Injection
Solution for injection · Zoetis UK Limited
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle36 days7 days—
Sheep24 days——
Tetroxy L.A. 200 mg/ml Oxytetracycline Solution for Injection
Solution for injection · Bimeda Animal Health Limited
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle39 days——
Sheep28 days——
Cyclofin 300 mg/ml + 20 mg/ml Solution for Injection for Cattle
Solution for injection · Dechra Regulatory B.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle35 days——

Recorded adverse effects

openFDA veterinary reports — the numbers are report counts, not a severity rate.

No adverse-effect data recorded for this ingredient yet.