Tiamulin Hydrogen Fumarate

Antibiotics

A pleuromutilin antibiotic that binds to the 50S ribosomal subunit, inhibiting protein synthesis. Particularly effective against Mycoplasma, Brachyspira, and Gram-positive bacteria.

Drug class
Antibiotics
Registered species
3
Recorded effects
0
Related products
3

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

A pleuromutilin antibiotic that binds to the 50S ribosomal subunit, inhibiting protein synthesis. Particularly effective against Mycoplasma, Brachyspira, and Gram-positive bacteria.

Indications

  • Swine dysentery caused by Brachyspira
  • Mycoplasma pneumonia in pigs and poultry

Contraindications & warnings

  • Serious interaction with ionophores (monensin, salinomycin, narasin) that may cause severe or fatal toxicity — concurrent or closely-spaced administration is prohibited
  • Hypersensitivity to the substance

Drug interactions

  • The fundamental interaction with ionophores noted above is the most clinically important

Prudent use of antibiotics

Prescribed based on diagnosis and susceptibility testing where possible, to limit antibiotic resistance.

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Denagard 10% w/w Premix for Medicated Feeding Stuff for Pigs, Chickens, Turkeys and Rabbits
Premix for medicated feeding stuff · Elanco Europe Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens1 days—zero
Turkeys4 days——
Rabbitszero——
Denagard 12.5% w/v Concentrate for Oral Solution
Oral solution · Elanco Europe Ltd
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens2 days—zero
Turkeys5 days——
Tialin 125 mg/ml Solution for Use in Drinking Water for Pigs, Chickens and Turkeys
Solution for use in drinking water · Dechra Regulatory B.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens2 days—zero
Turkeys6 days——

Recorded adverse effects

openFDA veterinary reports — the numbers are report counts, not a severity rate.

No adverse-effect data recorded for this ingredient yet.