A bacteriostatic macrolide antibiotic. It binds to the 50S ribosomal subunit, preventing protein synthesis. It is effective against Gram-positive bacteria and Mycoplasma.

Drug class
Antibiotics
Registered species
4
Recorded effects
0
Related products
6

Pharmacological information

A class-level scientific overview for general reference — no doses. The ultimate reference is always the locally approved product leaflet and consultation with a veterinarian.

Mechanism of action

A bacteriostatic macrolide antibiotic. It binds to the 50S ribosomal subunit, preventing protein synthesis. It is effective against Gram-positive bacteria and Mycoplasma.

Indications

  • Respiratory infections caused by susceptible bacteria
  • Mycoplasma infections in poultry and pigs
  • Proliferative enteropathy in pigs

Contraindications & warnings

  • Not to be given to horses — may cause a potentially fatal colitis
  • Hypersensitivity to macrolides

Drug interactions

  • Antagonism with lincosamides and phenicols due to competition for the same binding site

Prudent use of antibiotics

Prescribed based on diagnosis and susceptibility testing where possible, to limit antibiotic resistance.

Withdrawal periods

Note: Source: UK Veterinary Medicines Directorate (VMD). The figures are a guidance reference that may differ from the product registered in your country — always verify the locally approved leaflet and consult a veterinarian before slaughter or consuming products.
Pharmasin 1g/g Granules for Use in Drinking Water for Pigs, Chickens, Turkeys and Calves
Granules for use in drinking water · Huvepharma NV
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle12 days——
Chickens1 days—zero
Turkeys2 days—zero
Pharmasin 100000 IU/g Premix for Medicated Feeding Stuff for Pigs, Broilers and Pullets
Premix for medicated feeding stuff · Huvepharma N.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens1 days——
Pharmasin 250000 IU/g Premix for Medicated Feeding Stuff for Pigs, Broilers and Pullets
Premix for medicated feeding stuff · Huvepharma N.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens1 days——
Tylovectin 200 Solution for Injection for Cattle, Goats and Pigs
Solution for injection · Huvepharma N.V.
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle28 days108 hours—
Goats42 days108 hours—
Tylan 200, 200 mg/ml Solution for Injection
Solution for injection · Elanco GmbH
SPC leaflet ↗
SpeciesMeatMilkEggs
Cattle28 days108 hours—
Tylan G250 Premix for Medicated Feedingstuff
Premix for medicated feeding stuff · Elanco GmbH
SPC leaflet ↗
SpeciesMeatMilkEggs
Chickens1 days——

Recorded adverse effects

openFDA veterinary reports — the numbers are report counts, not a severity rate.

No adverse-effect data recorded for this ingredient yet.